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CNA2016

The Nuclear Connection to Combating the Zika Virus

A team of experts at the IAEA is launching a new fight against Zika and it’s totally nuclear.

It’s an astonishing fact. One million people have already been affected by the Zika virus, a number that could quadruple by the end of this year.

zikavirus

The World Health Organization (WHO) issued a global emergency on the virus and recent reports indicated that it has spread its way into North America. Reports of over 100 cases have already surfaced in the United States.

The Zika virus is not new. It was first discovered in Uganda back in the 1940s and is named after the forest in which it was found. The virus is spread through a mosquito known as Aedes aegypti.

Symptoms can include mild fevers, skin rashes, joint pain and headaches. But far worse, the virus has been linked to brain damage in babies and, according to French researchers, can also lead to brain infections in adults.

The procedure is called the sterile insect technique (SIT) and it’s been around for over 50 years. Very effective in addressing insect pests, the technique requires using a small dose of radiation to make insects infertile. It has been proven successful in other pest insects, suppressing or eradicating them all together. However, this will be first time that the SIT technique will be applied to fight human disease.

“Think of it as a method of birth control. We produce sterile male mosquitos using radiation that sterilizes the sperm in the male mosquito,” says Rosemary Lees, a medical entomologist with the IAEA. “When we release a large number of these males we flood a region with sterile males so that the wild females are more likely to mate with them.”

Since female mosquitos usually only mate once, mating with infertile males would stop the further reproduction of Aedes mosquitos.

The SIT technique relies on something known as Cobalt-60, a radioactive isotope that is currently used to sterilize 40 per cent of the world’s medical devices. In Canada Cobalt-60 is harvested from Bruce Power and processed by Nordion.

“Cobalt-60 from our reactors already plays a major role in keeping single-use medical equipment safely sterilized, and with it now helping to stop the spread of diseases like Zika virus the world’s population continues to benefit from it,” said James Scongack, Vice President, Corporate Affairs, Bruce Power. “We look forward to working with Nordion to continue safely harvesting Cobalt-60 during our planned maintenance outages so it can help prevent disease across the world.”

The second half of the program involves understanding the wild mosquito environment through trapping mosquitos. The idea is that if researchers know how many wild mosquitoes there are, they will know how many to release. The hope is that if enough wild mosquitos are trapped and sterile ones breed, that the spread of the virus will cease.

“We are trying to remove the vector. Think of Zika transmission as a triangle. People, virus and the mosquito. By removing one of the three you can stop the transmission,” according to Jeremie Gilles, head of the mosquito group with the IAEA.

The WHO has declared the Zika virus a public health emergency and has advised all pregnant women to avoid affected areas. This is only the fourth time in history that this has happened since International Heath Regulations (IHR) came into place in 2007.

The work being done at the IAEA through the use of nuclear technology may be able to stop the spread of what could soon be a global pandemic in its tracks.

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Cancer and Nuclear Medicine

Cancer and Nuclear Medicine Infographic - English

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Le cancer et la médecine nucléaire

Cancer and Nuclear Medicine Infographic - French